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Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius.
Rosenfeld, Jeffrey A; Reeves, Darryl; Brugler, Mercer R; Narechania, Apurva; Simon, Sabrina; Durrett, Russell; Foox, Jonathan; Shianna, Kevin; Schatz, Michael C; Gandara, Jorge; Afshinnekoo, Ebrahim; Lam, Ernest T; Hastie, Alex R; Chan, Saki; Cao, Han; Saghbini, Michael; Kentsis, Alex; Planet, Paul J; Kholodovych, Vladyslav; Tessler, Michael; Baker, Richard; DeSalle, Rob; Sorkin, Louis N; Kolokotronis, Sergios-Orestis; Siddall, Mark E; Amato, George; Mason, Christopher E.
Afiliación
  • Rosenfeld JA; Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA.
  • Reeves D; Division of Invertebrate Zoology, American Museum of Natural History, New York, New York 10024, USA.
  • Brugler MR; Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey 08908, USA.
  • Narechania A; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10065, USA.
  • Simon S; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, New York 10065, USA.
  • Durrett R; Tri-Institutional Training Program in Computational Biology and Medicine, New York, New York 10065, USA.
  • Foox J; Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA.
  • Shianna K; Division of Invertebrate Zoology, American Museum of Natural History, New York, New York 10024, USA.
  • Schatz MC; Biological Sciences Department, NYC College of Technology (CUNY), Brooklyn, New York 11201, USA.
  • Gandara J; Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA.
  • Afshinnekoo E; Division of Invertebrate Zoology, American Museum of Natural History, New York, New York 10024, USA.
  • Lam ET; Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA.
  • Hastie AR; Biosystematics, Wageningen University, Wageningen 6708 PB, The Netherlands.
  • Chan S; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10065, USA.
  • Cao H; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, New York 10065, USA.
  • Saghbini M; Sackler Institute for Comparative Genomics, American Museum of Natural History, New York, New York 10024, USA.
  • Kentsis A; Division of Invertebrate Zoology, American Museum of Natural History, New York, New York 10024, USA.
  • Planet PJ; Illumina Inc. 5200 Illumina Way, San Diego, California 92122, USA.
  • Kholodovych V; Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
  • Tessler M; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10065, USA.
  • Baker R; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, New York 10065, USA.
  • DeSalle R; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10065, USA.
  • Sorkin LN; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, New York, New York 10065, USA.
  • Kolokotronis SO; BioNanoGenomics Inc. 9640 Towne Centre Drive Ste. 100, San Diego, California 92121, USA.
  • Siddall ME; BioNanoGenomics Inc. 9640 Towne Centre Drive Ste. 100, San Diego, California 92121, USA.
  • Amato G; BioNanoGenomics Inc. 9640 Towne Centre Drive Ste. 100, San Diego, California 92121, USA.
  • Mason CE; BioNanoGenomics Inc. 9640 Towne Centre Drive Ste. 100, San Diego, California 92121, USA.
Nat Commun ; 7: 10164, 2016 Feb 02.
Article en En | MEDLINE | ID: mdl-26836631
ABSTRACT
The common bed bug (Cimex lectularius) has been a persistent pest of humans for thousands of years, yet the genetic basis of the bed bug's basic biology and adaptation to dense human environments is largely unknown. Here we report the assembly, annotation and phylogenetic mapping of the 697.9-Mb Cimex lectularius genome, with an N50 of 971 kb, using both long and short read technologies. A RNA-seq time course across all five developmental stages and male and female adults generated 36,985 coding and noncoding gene models. The most pronounced change in gene expression during the life cycle occurs after feeding on human blood and included genes from the Wolbachia endosymbiont, which shows a simultaneous and coordinated host/commensal response to haematophagous activity. These data provide a rich genetic resource for mapping activity and density of C. lectularius across human hosts and cities, which can help track, manage and control bed bug infestations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Chinches / Regulación del Desarrollo de la Expresión Génica / Estadios del Ciclo de Vida Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Chinches / Regulación del Desarrollo de la Expresión Génica / Estadios del Ciclo de Vida Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos