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Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes.
Geny, Sylvain; Moreno, Pedro M D; Krzywkowski, Tomasz; Gissberg, Olof; Andersen, Nicolai K; Isse, Abdirisaq J; El-Madani, Amro M; Lou, Chenguang; Pabon, Y Vladimir; Anderson, Brooke A; Zaghloul, Eman M; Zain, Rula; Hrdlicka, Patrick J; Jørgensen, Per T; Nilsson, Mats; Lundin, Karin E; Pedersen, Erik B; Wengel, Jesper; Smith, C I Edvard.
Afiliación
  • Geny S; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.
  • Moreno PM; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden INEB-Instituto de Engenharia Biomedica, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal.
  • Krzywkowski T; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, SE-171 21, Sweden.
  • Gissberg O; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.
  • Andersen NK; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • Isse AJ; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • El-Madani AM; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • Lou C; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • Pabon YV; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.
  • Anderson BA; Department of Chemistry, University of Idaho, Moscow, ID 83844, USA.
  • Zaghloul EM; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.
  • Zain R; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden Centre for Rare Diseases, Department of Clinical Genetics, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
  • Hrdlicka PJ; Department of Chemistry, University of Idaho, Moscow, ID 83844, USA.
  • Jørgensen PT; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • Nilsson M; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, SE-171 21, Sweden.
  • Lundin KE; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden.
  • Pedersen EB; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • Wengel J; Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, Nucleic Acid Centre, University of Southern Denmark, 5230 Odense, Denmark.
  • Smith CI; Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center, Karolinska University Hospital Huddinge, SE-141 86 Stockholm, Sweden edvard.smith@ki.se.
Nucleic Acids Res ; 44(5): 2007-19, 2016 Mar 18.
Article en En | MEDLINE | ID: mdl-26857548
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oligonucleótidos / ADN Bacteriano / ADN Superhelicoidal / Oligonucleótidos Antisentido / Glicina Idioma: En Revista: Nucleic Acids Res Año: 2016 Tipo del documento: Article País de afiliación: Suecia
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oligonucleótidos / ADN Bacteriano / ADN Superhelicoidal / Oligonucleótidos Antisentido / Glicina Idioma: En Revista: Nucleic Acids Res Año: 2016 Tipo del documento: Article País de afiliación: Suecia