Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes.

Imgenberg-Kreuz, Juliana; Sandling, Johanna K; Almlöf, Jonas Carlsson; Nordlund, Jessica; Signér, Linnea; Norheim, Katrine Braekke; Omdal, Roald; Rönnblom, Lars; Eloranta, Maija-Leena; Syvänen, Ann-Christine; Nordmark, Gunnel

Imgenberg-Kreuz, Juliana; Sandling, Johanna K; Almlöf, Jonas Carlsson; Nordlund, Jessica; Signér, Linnea; Norheim, Katrine Braekke; Omdal, Roald; Rönnblom, Lars; Eloranta, Maija-Leena; Syvänen, Ann-Christine; Nordmark, Gunnel.

Afiliación

Imgenberg-Kreuz J; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Sandling JK; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Almlöf JC; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Nordlund J; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Signér L; Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Norheim KB; Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway.
Omdal R; Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, Stavanger, Norway.
Rönnblom L; Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Eloranta ML; Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Syvänen AC; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
Nordmark G; Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

Ann Rheum Dis ; 75(11): 2029-2036, 2016 Nov.

Article en En | MEDLINE | ID: mdl-26857698

Asunto(s)

Metilación de ADN; Epigénesis Genética; Interferones/genética; Síndrome de Sjögren/genética; 2',5'-Oligoadenilato Sintetasa/genética; Adulto; Anciano; Antígenos/genética; Antígenos CD19/genética; Estudios de Casos y Controles; Proteínas del Citoesqueleto/genética; Femenino; Expresión Génica; Estudio de Asociación del Genoma Completo; Humanos; Masculino; Persona de Mediana Edad; Proteínas de Resistencia a Mixovirus/genética; Proteínas de Neoplasias/genética; Poli(ADP-Ribosa) Polimerasas/genética; Glándulas Salivales Menores/patología; Síndrome de Sjögren/sangre; Síndrome de Sjögren/patología

Palabras clave

Autoimmunity; B cells; Gene Polymorphism; Sjøgren's Syndrome

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Sjögren / Interferones / Metilación de ADN / Epigénesis Genética Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Año: 2016 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google