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A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening.
Noble, Christian G; Lim, Siew Pheng; Arora, Rishi; Yokokawa, Fumiaki; Nilar, Shahul; Seh, Cheah Chen; Wright, S Kirk; Benson, Timothy E; Smith, Paul W; Shi, Pei-Yong.
Afiliación
  • Noble CG; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670, christian.noble@novartis.com.
  • Lim SP; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670.
  • Arora R; the Novartis Institutes for BioMedical Research Inc., Cambridge, Massachusetts 02139, and.
  • Yokokawa F; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670.
  • Nilar S; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670.
  • Seh CC; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670.
  • Wright SK; the Novartis Institutes for BioMedical Research Inc., Cambridge, Massachusetts 02139, and.
  • Benson TE; the Novartis Institutes for BioMedical Research Inc., Cambridge, Massachusetts 02139, and.
  • Smith PW; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670.
  • Shi PY; From the Novartis Institute for Tropical Diseases, 05-01 Chromos, Singapore 138670, the Department of Biochemistry and Molecular Biology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, Texas 77555 peshi@utmb.edu.
J Biol Chem ; 291(16): 8541-8, 2016 Apr 15.
Article en En | MEDLINE | ID: mdl-26872970

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / ARN Polimerasas Dirigidas por ADN / Virus del Dengue Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / ARN Polimerasas Dirigidas por ADN / Virus del Dengue Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos