Novel effects of FTY720 on perinuclear reorganization of keratin network induced by sphingosylphosphorylcholine: Involvement of protein phosphatase 2A and G-protein-coupled receptor-12.

Park, Mi Kyung; Park, Soyeun; Kim, Hyun Ji; Kim, Eun Ji; Kim, So Yeon; Kang, Gyeoung Jin; Byun, Hyun Jung; Kim, Sang Hee; Lee, Ho; Lee, Chang Hoon

Park, Mi Kyung; Park, Soyeun; Kim, Hyun Ji; Kim, Eun Ji; Kim, So Yeon; Kang, Gyeoung Jin; Byun, Hyun Jung; Kim, Sang Hee; Lee, Ho; Lee, Chang Hoon.

Afiliación

Park MK; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea.
Park S; College of Pharmacy, Keimyung University, Daegu 704-701, Republic of Korea.
Kim HJ; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea.
Kim EJ; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea.
Kim SY; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea.
Kang GJ; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea.
Byun HJ; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea.
Kim SH; College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea.
Lee H; National Cancer Center, Goyang 10408, Republic of Korea.
Lee CH; BK21PLUS R-FIND Team, College of Pharmacy, Dongguk University, Seoul 100-715, Republic of Korea. Electronic address: uatheone@dongguk.edu.

Eur J Pharmacol ; 775: 86-95, 2016 Mar 15.

Article en En | MEDLINE | ID: mdl-26872988

Asunto(s)

Clorhidrato de Fingolimod/farmacología; Queratina-8/metabolismo; Organofosfatos/farmacología; Fosforilcolina/análogos & derivados; Proteína Fosfatasa 2/metabolismo; Receptores Acoplados a Proteínas G/metabolismo; Esfingosina/análogos & derivados; Línea Celular; Movimiento Celular/efectos de los fármacos; Humanos; Fosforilación/efectos de los fármacos; Fosforilcolina/farmacología; ARN Interferente Pequeño/genética; Receptores Acoplados a Proteínas G/genética; Esfingosina/farmacología

Palabras clave

Elastic constant; FTY720; GPR12; Keratin 8 reorganization; Protein phosphatase 2A; Sphingosylphosphorylcholine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Organofosfatos / Fosforilcolina / Esfingosina / Receptores Acoplados a Proteínas G / Queratina-8 / Proteína Fosfatasa 2 / Clorhidrato de Fingolimod Límite: Humans Idioma: En Revista: Eur J Pharmacol Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos

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