A GPCR Handles Bacterial Sensing in Chemotaxis and Phagocytosis.

Senoo, Hiroshi; Sesaki, Hiromi; Iijima, Miho

Senoo, Hiroshi; Sesaki, Hiromi; Iijima, Miho.

Afiliación

Senoo H; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Sesaki H; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Iijima M; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: miijima@jhmi.edu.

Dev Cell ; 36(4): 354-6, 2016 Feb 22.

Article en En | MEDLINE | ID: mdl-26906729

RESUMEN

In this issue of Developmental Cell, Pan et al. (2016) identified in cells of the social amoeba Dictyostelium a G protein-coupled receptor (GPCR) that recognizes a chemoattractant secreted by bacteria. This work uncovers a mechanism by which a single GPCR mediates pseudopod extension during cell migration and bacterial engulfment.

Asunto(s)

Quimiotaxis/fisiología; Dictyostelium/metabolismo; Ácido Fólico/metabolismo; Fagocitosis/fisiología; Receptores Acoplados a Proteínas G/metabolismo; Animales

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fagocitosis / Quimiotaxis / Receptores Acoplados a Proteínas G / Dictyostelium / Ácido Fólico Límite: Animals Idioma: En Revista: Dev Cell Asunto de la revista: EMBRIOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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