&#945;/ß-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli.

Zhao, Shangang; Poursharifi, Pegah; Mugabo, Yves; Levens, Emily J; Vivot, Kevin; Attane, Camille; Iglesias, Jose; Peyot, Marie-Line; Joly, Erik; Madiraju, S R Murthy; Prentki, Marc

α/ß-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli.

Zhao, Shangang; Poursharifi, Pegah; Mugabo, Yves; Levens, Emily J; Vivot, Kevin; Attane, Camille; Iglesias, Jose; Peyot, Marie-Line; Joly, Erik; Madiraju, S R Murthy; Prentki, Marc.

Afiliación

Zhao S; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Poursharifi P; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Mugabo Y; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Levens EJ; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Vivot K; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Attane C; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Iglesias J; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Peyot ML; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Joly E; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Madiraju SR; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.
Prentki M; Departments of Nutrition, Biochemistry and Molecular Medicine, Montreal Diabetes Research Center, CRCHUM and Université de Montréal, Montreal, QC, Canada.

Mol Metab ; 4(12): 940-50, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26909310

Palabras clave

1-OG, 1-oleoylglycerol; 1-PG, 1-palmitoylglycerol; 1-SG, 1-stearoylglycerol; ABHD6, α/ß-hydrolase domain-6; ATGL, adipose triglyceride lipase; BKO, ß cell specific ABHD6-knockout; Carb, carbamylcholine; Cytosolic Ca2+; DAG, diacylglycerol; FFA, free fatty acid; Flox, flox/flox; GL/FFA, glycerolipid/ free fatty acid; GLP1, glucagon-like peptide 1; GPCR, G-protein coupled receptor; GSIS, glucose stimulated insulin secretion; HSL, hormone sensitive lipase; Insulin secretion; KO, knockout; Kic, α-ketoisocaproate; MAG, monoacylglycerol; Monoacylglycerol; OGTT, oral glucose tolerance test; Pancreatic islets; ROS, reactive oxygen species; TG, triacylglycerol; WT, wild type; α/ß-Hydrolase domain-6

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Mol Metab Año: 2015 Tipo del documento: Article País de afiliación: Canadá

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