Effects of a medetomidine-ketamine combination on Schirmer tear test I results of clinically normal cats.
Am J Vet Res
; 77(3): 310-4, 2016 Mar.
Article
en En
| MEDLINE
| ID: mdl-26919603
ABSTRACT
OBJECTIVE:
To evaluate the effects of a medetomidine-ketamine combination on tear production of clinically normal cats by use of the Schirmer tear test (STT) 1 before and during anesthesia and after reversal of medetomidine with atipamezole. ANIMALS 40 client-owned crossbred domestic shorthair cats (23 males and 17 females; age range, 6 to 24 months). PROCEDURES A complete physical examination, CBC, and ophthalmic examination were performed on each cat. Cats with no abnormalities on physical and ophthalmic examinations were included in the study. Cats were allocated into 2 groups a control group (n = 10 cats) anesthetized by administration of a combination of medetomidine hydrochloride (80 µg/kg) and ketamine hydrochloride (5 mg/kg), and an experimental group (30) anesthetized with the medetomidine-ketamine combination and reversal by administration of atipamezole. Tear production of both eyes of each cat was measured by use of the STT I before anesthesia, 15 minutes after the beginning of anesthesia, and 15 minutes after administration of atipamezole.RESULTS:
Anesthesia with a medetomidine-ketamine combination of cats with no ophthalmic disease caused a significant decrease in tear production. The STT I values returned nearly to preanesthetic values within 15 minutes after reversal with atipamezole, whereas the STT I values for the control group were still low at that point. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that a tear substitute should be administered to eyes of cats anesthetized with a medetomidine-ketamine combination from the time of anesthetic administration until at least 15 minutes after administration of atipamezole.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Lágrimas
/
Gatos
/
Medetomidina
/
Hipnóticos y Sedantes
/
Ketamina
/
Anestésicos Disociativos
Límite:
Animals
Idioma:
En
Revista:
Am J Vet Res
Año:
2016
Tipo del documento:
Article