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Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects.
Sudiwala, Sonia; De Castro, Sandra C P; Leung, Kit-Yi; Brosnan, John T; Brosnan, Margaret E; Mills, Kevin; Copp, Andrew J; Greene, Nicholas D E.
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  • Sudiwala S; Newlife Birth Defects Research Centre and Developmental Biology & Cancer Programme, Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • De Castro SC; Newlife Birth Defects Research Centre and Developmental Biology & Cancer Programme, Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Leung KY; Newlife Birth Defects Research Centre and Developmental Biology & Cancer Programme, Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Brosnan JT; Department of Biochemistry, Memorial University of Newfoundland, St John's, NL, A1B3X9, Canada.
  • Brosnan ME; Department of Biochemistry, Memorial University of Newfoundland, St John's, NL, A1B3X9, Canada.
  • Mills K; Genetics & Genomic Medicine Programme, Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Copp AJ; Newlife Birth Defects Research Centre and Developmental Biology & Cancer Programme, Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Greene ND; Newlife Birth Defects Research Centre and Developmental Biology & Cancer Programme, Institute of Child Health, University College London, London, WC1N 1EH, UK. Electronic address: n.greene@ucl.ac.uk.
Biochimie ; 126: 63-70, 2016 Jul.
Article en En | MEDLINE | ID: mdl-26924399
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disrafia Espinal / Ácido Fólico / Formiatos / Nucleótidos Límite: Animals Idioma: En Revista: Biochimie Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Disrafia Espinal / Ácido Fólico / Formiatos / Nucleótidos Límite: Animals Idioma: En Revista: Biochimie Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Francia