Determination of a potential antitumor quassinoid in rat plasma by UPLC-MS/MS and its application in a pharmacokinetic study.

Zhang, Qiang; Yuan, Yonghui; Cui, Jianchun; Xiao, Tingting; Deng, Zhipeng; Jiang, Daqing

Zhang, Qiang; Yuan, Yonghui; Cui, Jianchun; Xiao, Tingting; Deng, Zhipeng; Jiang, Daqing.

Afiliación

Zhang Q; Breast Surgery, Liaoning Cancer Hospital & Institute, Shenyang 110042, China.
Yuan Y; Department of Infection, Liaoning Cancer Hospital & Institute, Shenyang 110042, China.
Cui J; Department of Endocrine Surgery, the People's Hospital of Liaoning Province, Shenyang 110016, China.
Xiao T; School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Deng Z; Institute of Materia Medica, Shandong Academy of Medical Sciences, Jinan 250062, China. Electronic address: depon2005@126.com.
Jiang D; Breast Surgery, Liaoning Cancer Hospital & Institute, Shenyang 110042, China. Electronic address: daqingjiang11@sina.com.

J Pharm Biomed Anal ; 124: 143-148, 2016 May 30.

Article en En | MEDLINE | ID: mdl-26945636

Asunto(s)

Antineoplásicos/farmacocinética; Cromatografía Liquida/métodos; Cuassinas/farmacocinética; Espectrometría de Masas en Tándem/métodos; Animales; Antineoplásicos/sangre; Cuassinas/sangre; Ratas; Reproducibilidad de los Resultados

Palabras clave

Brusatol; Pharmacokinetic study; Quassinoid; Rat plasma; UPLCMS/MS

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatografía Liquida / Cuassinas / Espectrometría de Masas en Tándem / Antineoplásicos Límite: Animals Idioma: En Revista: J Pharm Biomed Anal Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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