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Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4.
Warfield, Kelly L; Plummer, Emily M; Sayce, Andrew C; Alonzi, Dominic S; Tang, William; Tyrrell, Beatrice E; Hill, Michelle L; Caputo, Alessandro T; Killingbeck, Sarah S; Beatty, P Robert; Harris, Eva; Iwaki, Ren; Kinami, Kyoko; Ide, Daisuke; Kiappes, J L; Kato, Atsushi; Buck, Michael D; King, Kevin; Eddy, William; Khaliq, Mansoora; Sampath, Aruna; Treston, Anthony M; Dwek, Raymond A; Enterlein, Sven G; Miller, Joanna L; Zitzmann, Nicole; Ramstedt, Urban; Shresta, Sujan.
Afiliación
  • Warfield KL; Emergent Virology LLC, Gaithersburg, MD 20879, USA. Electronic address: warfieldk@ebsi.com.
  • Plummer EM; La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: Emily.plummer@gmail.com.
  • Sayce AC; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: andrew.sayce@bioch.ox.ac.uk.
  • Alonzi DS; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: dominic.alonzi@bioch.ox.ac.uk.
  • Tang W; La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: wtang@lji.org.
  • Tyrrell BE; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: beatrice.tyrrell@bioch.ox.ac.uk.
  • Hill ML; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: michelle.hill@bioch.ox.ac.uk.
  • Caputo AT; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: alessandro.caputo@stx.ox.ac.uk.
  • Killingbeck SS; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California-Berkeley, Berkeley, CA, USA. Electronic address: sskillingbeck@ucdavis.edu.
  • Beatty PR; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California-Berkeley, Berkeley, CA, USA. Electronic address: prbeatty@berkeley.edu.
  • Harris E; Division of Infectious Diseases and Vaccinology, School of Public Health, University of California-Berkeley, Berkeley, CA, USA. Electronic address: eharris@berkeley.edu.
  • Iwaki R; Department of Hospital Pharmacy, University of Toyama, Toyama, Japan. Electronic address: r-iwaki@fujichemical.co.jp.
  • Kinami K; Department of Hospital Pharmacy, University of Toyama, Toyama, Japan. Electronic address: s1160215@ems.u-toyama.ac.jp.
  • Ide D; Department of Hospital Pharmacy, University of Toyama, Toyama, Japan. Electronic address: s1260204@ems.u-toyama.ac.jp.
  • Kiappes JL; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: john.kiappes@bioch.ox.ac.uk.
  • Kato A; Department of Hospital Pharmacy, University of Toyama, Toyama, Japan. Electronic address: kato@med.u-toyama.ac.jp.
  • Buck MD; La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: mdsbuck@gmail.com.
  • King K; La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: kevindalesamuelking@gmail.com.
  • Eddy W; La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: william.e.eddy@gmail.com.
  • Khaliq M; Emergent Virology LLC, Gaithersburg, MD 20879, USA. Electronic address: khlaliqm@ebsi.com.
  • Sampath A; Emergent Virology LLC, Gaithersburg, MD 20879, USA. Electronic address: sampatha1@ebsi.com.
  • Treston AM; Emergent Virology LLC, Gaithersburg, MD 20879, USA. Electronic address: trestona@ebsi.com.
  • Dwek RA; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: raymond.dwek@exeter.ox.ac.uk.
  • Enterlein SG; Integrated Biotherapeutics, Gaithersburg, MD 20878, USA. Electronic address: sven@integratedbiotherapeutics.com.
  • Miller JL; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: joanna.miller@bioch.ox.ac.uk.
  • Zitzmann N; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, United Kingdom. Electronic address: nicole.zitzmann@bioch.ox.ac.uk.
  • Ramstedt U; Unither Virology LLC, Silver Spring, MD 20910, USA. Electronic address: urban_ramstedt@yahoo.com.
  • Shresta S; La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: sujan@lji.org.
Antiviral Res ; 129: 93-98, 2016 May.
Article en En | MEDLINE | ID: mdl-26946111
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / 1-Desoxinojirimicina / Dengue Grave / Virus del Dengue / Alfa-Glucosidasas / Inhibidores de Glicósido Hidrolasas Límite: Animals / Humans Idioma: En Revista: Antiviral Res Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / 1-Desoxinojirimicina / Dengue Grave / Virus del Dengue / Alfa-Glucosidasas / Inhibidores de Glicósido Hidrolasas Límite: Animals / Humans Idioma: En Revista: Antiviral Res Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos