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Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells.
Jiang, Shanshan; Fan, Jiajun; Wang, Qian; Ju, Dianwen; Feng, Meiqing; Li, Jiyang; Guan, Zhong-Bin; An, Duopeng; Wang, Xin; Ye, Li.
Afiliación
  • Jiang S; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Fan J; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Wang Q; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Ju D; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Feng M; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Li J; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Guan ZB; Shanghai Institute For Food And Drug Control, Shanghai, China.
  • An D; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Wang X; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Ye L; Department of Biosynthesis & Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China. Electronic address: yelil@fudan.edu.cn.
Phytomedicine ; 23(3): 243-52, 2016 Mar 15.
Article en En | MEDLINE | ID: mdl-26969378
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Leucemia Mielógena Crónica BCR-ABL Positiva / Transducción de Señal / Especies Reactivas de Oxígeno / Diosgenina / Serina-Treonina Quinasas TOR Límite: Animals / Humans Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Leucemia Mielógena Crónica BCR-ABL Positiva / Transducción de Señal / Especies Reactivas de Oxígeno / Diosgenina / Serina-Treonina Quinasas TOR Límite: Animals / Humans Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania