Marked Improvement with Pirfenidone in a Patient with Idiopathic Pulmonary Fibrosis.
Intern Med
; 55(6): 657-61, 2016.
Article
en En
| MEDLINE
| ID: mdl-26984086
A man in his mid-60's with idiopathic pulmonary fibrosis and hepatitis B-related liver cirrhosis developed exertional dyspnea and a dry cough lasting for three months. High-resolution computed tomography (HRCT) showed increasing bilateral ground-glass opacity superimposed on the usual interstitial pneumonia pattern. Six months after starting pirfenidone therapy, the partial pressure of arterial oxygen at rest increased from 81 to 101 torr, the predicted forced vital capacity (FVC) value increased from 75% to 94% and the ground-glass opacity on HRCT improved. The FVC value was subsequently maintained near or above baseline for 43 months. We concluded that our patient was a super-responder to pirfenidone therapy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piridonas
/
Tomografía Computarizada por Rayos X
/
Capacidad Vital
/
Antiinflamatorios no Esteroideos
/
Fibrosis Pulmonar Idiopática
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Japón