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Crystal structure of 3-{5-[3-(4-fluoro-phen-yl)-1-isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2-one ethanol monosolvate.
Rahman, Md Lutfor; Kulkarni, Ajaykumar D; Mohd Yusoff, Mashitah; Kwong, Huey Chong; Quah, Ching Kheng.
Afiliación
  • Rahman ML; University Malaysia Pahang, Faculty of Industrial Sciences and Technology, 26300 Gambang, Kuantan, Pahang, Malaysia.
  • Kulkarni AD; Department of Chemistry, KLS's Gogte Institute of Technology, Jnana Ganga, Udyambag, Belagavi-590008 Karnataka, India.
  • Mohd Yusoff M; University Malaysia Pahang, Faculty of Industrial Sciences and Technology, 26300 Gambang, Kuantan, Pahang, Malaysia.
  • Kwong HC; School of Chemical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
  • Quah CK; X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
Acta Crystallogr E Crystallogr Commun ; 72(Pt 3): 283-6, 2016 Mar 01.
Article en En | MEDLINE | ID: mdl-27006787
The title indolin-2-one compound, C28H23FN4O·C2H6O, crystallizes as a 1:1 ethanol solvate. The ethanol mol-ecule is disordered over two positions with refined site occupancies of 0.560 (14) and 0.440 (14). The pyrazole ring makes dihedral angles of 84.16 (10) and 85.33 (9)° with the indolin-2-one and indole rings, respectively, whereas the dihedral angle between indolin-2-one and indole rings is 57.30 (7)°. In the crystal, the components are linked by N-H⋯O and O-H⋯O hydrogen bonds, forming an inversion mol-ecule-solvate 2:2 dimer with R 4 (4)(12) ring motifs. The crystal structure is consolidated by π-π inter-action between pairs of inversion-related indolin-2-one rings [inter-planar spacing = 3.599 (2) Å].
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Crystallogr E Crystallogr Commun Año: 2016 Tipo del documento: Article País de afiliación: Malasia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Crystallogr E Crystallogr Commun Año: 2016 Tipo del documento: Article País de afiliación: Malasia Pais de publicación: Reino Unido