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Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain.
Frost, Jennifer M; DeGoey, David A; Shi, Lei; Gum, Rebecca J; Fricano, Meagan M; Lundgaard, Greta L; El-Kouhen, Odile F; Hsieh, Gin C; Neelands, Torben; Matulenko, Mark A; Daanen, Jerome F; Pai, Madhavi; Ghoreishi-Haack, Nayereh; Zhan, Cenchen; Zhang, Xu-Feng; Kort, Michael E.
Afiliación
  • Frost JM; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • DeGoey DA; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Shi L; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Gum RJ; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Fricano MM; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Lundgaard GL; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • El-Kouhen OF; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Hsieh GC; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Neelands T; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Matulenko MA; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Daanen JF; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Pai M; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Ghoreishi-Haack N; Aptinyx , 1801 Maple Avenue, No. 4300, Evanston, Illinois 60201, United States.
  • Zhan C; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Zhang XF; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
  • Kort ME; Research and Development, AbbVie , 1 North Waukegan Road, North Chicago, Illinois 60064, United States.
J Med Chem ; 59(7): 3373-91, 2016 Apr 14.
Article en En | MEDLINE | ID: mdl-27015369
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoartritis / Dolor / Pirroles / Bloqueadores de los Canales de Sodio / Imidazolidinas / Canal de Sodio Activado por Voltaje NAV1.7 / Analgésicos / Indazoles Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoartritis / Dolor / Pirroles / Bloqueadores de los Canales de Sodio / Imidazolidinas / Canal de Sodio Activado por Voltaje NAV1.7 / Analgésicos / Indazoles Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos