Paediatric infectious keratitis at tertiary referral centres in Vancouver, Canada.
Br J Ophthalmol
; 100(12): 1714-1718, 2016 Dec.
Article
en En
| MEDLINE
| ID: mdl-27030278
ABSTRACT
OBJECTIVE:
To report the clinical and microbiological profiles of paediatric patients with infectious keratitis in Vancouver, Canada.DESIGN:
In this observational case series, the microbiology results and medical records of 17 eyes with microbial keratitis in 16 children aged 17â years or younger were retrospectively reviewed. These patients had undergone corneal scraping between May 2006 and April 2011 at BC Children's Hospital or Vancouver General Hospital Eye Care Centre in Vancouver, British Columbia, Canada. Demographic information, clinical features, predisposing factors, results of microbiology studies, antibiotic susceptibilities, treatment course and outcomes were analysed.RESULTS:
The mean age of patients was 11±5.7â years (range 1-17â years) and the malefemale ratio was 1.41. Major predisposing factors were contact lens wear (6/17; 35%), and pre-existing ocular surface conditions including blepharitis (3/17; 18%) and Stevens-Johnson syndrome (3/17; 18%). Four patients had a previous corneal ulcer. The most commonly isolated microorganisms were Staphylococcus epidermidis and Acanthamoeba. Acanthamoeba was isolated in 67% of contact lens-related corneal ulcers, while the remaining 33% of contact lens-related corneal ulcers were associated with infection with Pseudomonas aeruginosa. Final visual acuity was better than 20/60 in 9 out of 16 patients (56%). Three patients subsequently required surgical management with either penetrating keratoplasty or deep anterior lamellar keratoplasty for treatment of corneal scarring.CONCLUSIONS:
Contact lens wear and pre-existing ocular surface conditions are significant risk factors for the development of infectious keratitis in our paediatric population. Knowledge of regional patterns of infection and susceptibility are essential in ensuring prompt treatment of this potentially sight-threatening condition.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Población Urbana
/
Infecciones del Ojo
/
Córnea
/
Centros de Atención Terciaria
/
Queratitis
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Br J Ophthalmol
Año:
2016
Tipo del documento:
Article
País de afiliación:
Canadá