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Identification and Characterization of BMS-955176, a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Antiviral Spectrum, and Gag Polymorphic Coverage.
Nowicka-Sans, Beata; Protack, Tricia; Lin, Zeyu; Li, Zhufang; Zhang, Sharon; Sun, Yongnian; Samanta, Himadri; Terry, Brian; Liu, Zheng; Chen, Yan; Sin, Ny; Sit, Sing-Yuen; Swidorski, Jacob J; Chen, Jie; Venables, Brian L; Healy, Matthew; Meanwell, Nicholas A; Cockett, Mark; Hanumegowda, Umesh; Regueiro-Ren, Alicia; Krystal, Mark; Dicker, Ira B.
Afiliación
  • Nowicka-Sans B; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Protack T; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Lin Z; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Li Z; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Zhang S; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Sun Y; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Samanta H; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Terry B; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Liu Z; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Chen Y; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Sin N; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Sit SY; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Swidorski JJ; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Chen J; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Venables BL; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Healy M; Bristol-Myers Squibb, Research and Development, Department of Genomics, Wallingford, Connecticut, USA.
  • Meanwell NA; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Cockett M; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Hanumegowda U; Bristol-Myers Squibb, Research and Development, Department of Preclinical Optimization, Wallingford, Connecticut, USA.
  • Regueiro-Ren A; Bristol-Myers Squibb, Research and Development, Department of Discovery Chemistry, Wallingford, Connecticut, USA.
  • Krystal M; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA.
  • Dicker IB; Bristol-Myers Squibb, Research and Development, Department of Virology, Wallingford, Connecticut, USA Ira.B.Dicker@viivhealthcare.com.
Antimicrob Agents Chemother ; 60(7): 3956-69, 2016 07.
Article en En | MEDLINE | ID: mdl-27090171

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: VIH-1 / Fármacos Anti-VIH / Productos del Gen gag del Virus de la Inmunodeficiencia Humana Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: VIH-1 / Fármacos Anti-VIH / Productos del Gen gag del Virus de la Inmunodeficiencia Humana Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos