[Multiple and successive treatment failures in a patient infected by Plasmodium falciparum in Cambodia and treated by dihydroartemisinin-piperaquine]. / Echecs thérapeutiques multiples et successifs chez un patient infecté par Plasmodium falciparum au Cambodge et traité par dihydroartémisinine-pipéraquine.
Bull Soc Pathol Exot
; 109(2): 87-90, 2016 May.
Article
en Fr
| MEDLINE
| ID: mdl-27100863
ABSTRACT
Cases of treatment failures following administration of artemisinin-based combination therapies (ACT) remain rare in malaria endemic areas. In Cambodia, however, failures of these treatments are now commonly observed. Usually, these post-treatment recurrences occur only once and a second course of the same treatment is sufficient to cure patients.We describe here an atypical case of a Plasmodium falciparum-infected patient manifesting several malaria recrudescence episodes following dihydroartemisinin-piperaquine (Eurartesim®) treatment. This case report illustrates the current issue of resistance to the latest generation of antimalarial drugs in Southeast Asia and highlights the difficulty in efficaciously fighting malaria in this region if new therapy remains unimplemented.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quinolinas
/
Malaria Falciparum
/
Artemisininas
/
Antimaláricos
Límite:
Humans
/
Male
/
Middle aged
País/Región como asunto:
Asia
Idioma:
Fr
Revista:
Bull Soc Pathol Exot
Año:
2016
Tipo del documento:
Article
País de afiliación:
Camboya