[High-dose short-term antibiotic therapy in bacteremia and infection in severely burned patients]. / Hochdosierte antibiotische Kurzzeittherapie der Bakteriämie und Sepsis bei Schwerbrandverletzten.
Wien Klin Wochenschr
; 101(7): 241-4, 1989 Mar 31.
Article
en De
| MEDLINE
| ID: mdl-2711697
ABSTRACT
60 to 70% of all late deaths in patients with severe burns are due to sepsis. Thus, treatment with antibiotics is essential in the overall management of such patients, which in our hospital is carried out according to the following principles 1. No prophylactic antibiotic treatment. 2. Careful evaluation of the bacterial spectrum of the burns, nasopharyngeal area, anal region, sputum and blood cultures. 3. In case of bacteriaemia we start high-dose combination therapy with two different, specific chemotherapeutic agents, given alternately every 4 to 6 hours. 4. In concordance with the clinical picture antibiotic therapy is discontinued as soon as three subsequent blood cultures remain sterile. Since 1980, 58 patients with severe burns (extent 20 to 90% of body surface) have been treated according to these principles. Mortality due to sepsis was low, namely 9.5% (2 out of 21 patients presenting with bacteriaemia), so that our method of treatment has proven to be effective.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infección de Heridas
/
Quemaduras
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Sepsis
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Quimioterapia Combinada
/
Antibacterianos
Límite:
Humans
Idioma:
De
Revista:
Wien Klin Wochenschr
Año:
1989
Tipo del documento:
Article
Pais de publicación:
AT
/
AUSTRIA
/
ÁUSTRIA