Application of adsorptive stripping voltammetry to the study of immunoglobulin A and its interaction with benzodiazepine drugs.

ABSTRACT

The adsorptive stripping voltammetric behaviour of immunoglobulin A has been optimised with respect to accumulation time, accumulation potential, scan rate and drop size and its interaction with benzodiazepine drugs in 0.05 M phosphate buffer (pH 7.4) has been studied. Immunoglobulin A was observed to form a strongly reducible complex with diazepam and a labile non-reducible complex with flurazepam.