Deferasirox AUC efficacy cutoff and role of pharmacogenetics.

Allegra, S; Cusato, J; De Francia, S; Massano, D; Piga, A; D'Avolio, A

Allegra, S; Cusato, J; De Francia, S; Massano, D; Piga, A; D'Avolio, A.

Afiliación

Allegra S; Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Unit of Infectious Diseases, Amedeo di Savoia Hospital University of TorinoCorso Svizzera 16410149 TurinItaly, University of Turin, 10149, Turin, Italy.
Cusato J; Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Unit of Infectious Diseases, Amedeo di Savoia Hospital University of TorinoCorso Svizzera 16410149 TurinItaly, University of Turin, 10149, Turin, Italy.
De Francia S; Department of Biological and Clinical Sciences, S. Luigi Gonzaga Hospital, University of Turin, 10043, Orbassano, TO, Italy.
Massano D; Department of Pediatrics, Centre for Microcitemie, S. Luigi Gonzaga Hospital, University of Turin, 10043, Orbassano, TO, Italy.
Piga A; Department of Pediatrics, Centre for Microcitemie, S. Luigi Gonzaga Hospital, University of Turin, 10043, Orbassano, TO, Italy.
D'Avolio A; Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Unit of Infectious Diseases, Amedeo di Savoia Hospital University of TorinoCorso Svizzera 16410149 TurinItaly, University of Turin, 10149, Turin, Italy. antonio.davolio@unito.it.

Eur J Clin Pharmacol ; 72(9): 1155-7, 2016 Sep.

Article en En | MEDLINE | ID: mdl-27193993

Asunto(s)

Benzoatos/farmacocinética; Benzoatos/uso terapéutico; Quelantes del Hierro/farmacocinética; Quelantes del Hierro/uso terapéutico; Triazoles/farmacocinética; Triazoles/uso terapéutico; Talasemia beta/tratamiento farmacológico; Área Bajo la Curva; Benzoatos/sangre; Deferasirox; Femenino; Genotipo; Humanos; Masculino; Farmacogenética; Polimorfismo de Nucleótido Simple; Resultado del Tratamiento; Triazoles/sangre; Talasemia beta/sangre; Talasemia beta/genética; Talasemia beta/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triazoles / Benzoatos / Quelantes del Hierro / Talasemia beta Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Eur J Clin Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Italia

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