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Rational design of a protein that binds integrin αvß3 outside the ligand binding site.
Turaga, Ravi Chakra; Yin, Lu; Yang, Jenny J; Lee, Hsiauwei; Ivanov, Ivaylo; Yan, Chunli; Yang, Hua; Grossniklaus, Hans E; Wang, Siming; Ma, Cheng; Sun, Li; Liu, Zhi-Ren.
Afiliación
  • Turaga RC; Department of Biology, Georgia State University, Atlanta, Georgia 30303, USA.
  • Yin L; Department of Biology, Georgia State University, Atlanta, Georgia 30303, USA.
  • Yang JJ; Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
  • Lee H; Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
  • Ivanov I; Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
  • Yan C; Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
  • Yang H; Department of Ophthalmology, Eye Center, Emory University, Atlanta, Georgia 30322, USA.
  • Grossniklaus HE; Department of Ophthalmology, Eye Center, Emory University, Atlanta, Georgia 30322, USA.
  • Wang S; Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
  • Ma C; Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA.
  • Sun L; Center for Diagnostics and Therapeutics, Amoytop Biotech Inc., Xiamen 361028, China.
  • Liu ZR; Department of Biology, Georgia State University, Atlanta, Georgia 30303, USA.
Nat Commun ; 7: 11675, 2016 05 31.
Article en En | MEDLINE | ID: mdl-27241473
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Apoptosis / Inhibidores de la Angiogénesis / Integrina alfaVbeta3 / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Apoptosis / Inhibidores de la Angiogénesis / Integrina alfaVbeta3 / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos