Ethnicity is an independent predictor of IVF-ICSI outcome: a study of 5,549 cycles in Spain and India.
Gynecol Endocrinol
; 32(10): 819-822, 2016 Oct.
Article
en En
| MEDLINE
| ID: mdl-27243388
ABSTRACT
AIM:
To determine the role of ethnicity on IVF/ICSI outcomes between Indian and white Caucasian women. SETTINGS ANDDESIGN:
Retrospective cohort study. MATERIALS ANDMETHODS:
White Caucasian and Indian women undergoing IVF/ICSI treatment cycles. Total 5549 self, non-donor, fresh IVF cycles conducted from January 2014 to March 2015, out of which, 4227 were white Caucasian and 1322 were Indian. Data were collected on baseline characteristics, IVF cycle parameters and outcomes. Ongoing pregnancy rate (OPR) was measured as main outcome.RESULTS:
Indian women differed significantly from white Caucasian women in baseline characteristics like age (30.6 ± 0.2 versus 37.6 ± 0.1 years; p < 0.001), BMI (22.3 ± 0.2 versus 26.6 ± 1.0 kg/m2; p < 0.05), duration of infertility (6.9 ± 3.0 versus 2.5 ± 0.1 years; p < 0.001) and antral follicle count (AFC) (8.9 ± 0.4 versus 7.5 ± 0.2; p < 0.001). Indian women had lower implantation rate (30.1% versus 39.6% p < 0.001) and OPR (35.1% versus 41.7% p < 0.001) compared with white Caucasian women. Regression analysis proved independent effect of ethnicity on OPR (OR 0.944; 95% CI 0.928-0.961 p < 0.001)Conclusions:
OPR was significantly lower among Indian ethnic group following IVF/ICSI suggest that ethnicity, like age, is a major and an independent predictor of IVF outcome.Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fertilización In Vitro
/
Evaluación de Resultado en la Atención de Salud
/
Infertilidad Femenina
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
País/Región como asunto:
Asia
/
Europa
Idioma:
En
Revista:
Gynecol Endocrinol
Asunto de la revista:
ENDOCRINOLOGIA
/
GINECOLOGIA
Año:
2016
Tipo del documento:
Article