Sensory Processing in Rhesus Monkeys: Developmental Continuity, Prenatal Treatment, and Genetic Influences.
Child Dev
; 88(1): 183-197, 2017 01.
Article
en En
| MEDLINE
| ID: mdl-27338151
ABSTRACT
Neonatal sensory processing (tactile and vestibular function) was tested in 78 rhesus macaques from two experiments. At ages 4-5 years, striatal dopamine D2 receptor binding was examined using positron emission tomography. At ages 5-7 years, adult sensory processing was assessed. Findings were (a) prenatal stress exposure yielded less optimal neonatal sensory processing; (b) animals carrying the short rh5-HTTLPR allele had less optimal neonatal sensory scores than monkeys homozygous for the long allele; (c) neonatal sensory processing was significantly related to striatal D2 receptor binding for carriers of the short allele, but not for animals homozygous for the long allele; and (d) there was moderate developmental continuity in sensory processing from the neonatal period to adulthood.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Efectos Tardíos de la Exposición Prenatal
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Estrés Psicológico
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Conducta Animal
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Depresores del Sistema Nervioso Central
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Receptores de Dopamina D2
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Etanol
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Proteínas de Transporte de Serotonina en la Membrana Plasmática
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Percepción del Tacto
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Macaca mulatta
Tipo de estudio:
Etiology_studies
Límite:
Animals
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Pregnancy
Idioma:
En
Revista:
Child Dev
Año:
2017
Tipo del documento:
Article