Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases.

Zhang, Wanyu; Lv, Yuhong; Xue, Yang; Wu, Chenxing; Yao, Kun; Zhang, Chuanbao; Jin, Qiang; Huang, Rong; Li, Jiuyi; Sun, Yingyu; Su, Xiaodong; Jiang, Tao; Fan, Xiaolong

Zhang, Wanyu; Lv, Yuhong; Xue, Yang; Wu, Chenxing; Yao, Kun; Zhang, Chuanbao; Jin, Qiang; Huang, Rong; Li, Jiuyi; Sun, Yingyu; Su, Xiaodong; Jiang, Tao; Fan, Xiaolong.

Afiliación

Zhang W; Laboratory of Neuroscience and Brain Development, Beijing Key Laboratory of Gene Resources and Molecular Development, Beijing Normal University, Beijing, China.
Lv Y; Laboratory of Neuroscience and Brain Development, Beijing Key Laboratory of Gene Resources and Molecular Development, Beijing Normal University, Beijing, China.
Xue Y; Current address: Department of Cell Biology, Hebei Medical University, Hebei, Shijiazhuang, China.
Wu C; Laboratory of Neuroscience and Brain Development, Beijing Key Laboratory of Gene Resources and Molecular Development, Beijing Normal University, Beijing, China.
Yao K; Department of Neurosurgery, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Zhang C; Department of Pathology, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Jin Q; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Huang R; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Li J; Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Sun Y; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Su X; Laboratory of Neuroscience and Brain Development, Beijing Key Laboratory of Gene Resources and Molecular Development, Beijing Normal University, Beijing, China.
Jiang T; Laboratory of Neuroscience and Brain Development, Beijing Key Laboratory of Gene Resources and Molecular Development, Beijing Normal University, Beijing, China.
Fan X; Laboratory of Neuroscience and Brain Development, Beijing Key Laboratory of Gene Resources and Molecular Development, Beijing Normal University, Beijing, China.

Oncotarget ; 7(37): 59098-59114, 2016 Sep 13.

Article en En | MEDLINE | ID: mdl-27385209

Asunto(s)

Glioma/genética; Péptidos y Proteínas de Señalización Intracelular/metabolismo; Proteínas de la Membrana/metabolismo; Proteínas del Tejido Nervioso/metabolismo; Neurofibromina 1/metabolismo; Fosfohidrolasa PTEN/metabolismo; Fosfoproteínas/metabolismo; Proteínas Tirosina Quinasas Receptoras/metabolismo; Adulto; Análisis por Conglomerados; Regulación Neoplásica de la Expresión Génica; Glioma/diagnóstico; Glioma/patología; Humanos; Péptidos y Proteínas de Señalización Intracelular/genética; Proteínas de la Membrana/genética; Estadificación de Neoplasias; Proteínas del Tejido Nervioso/genética; Neurofibromina 1/genética; Fosfohidrolasa PTEN/genética; Fosfatidilinositol 3-Quinasas/metabolismo; Fosfoproteínas/genética; Receptor Cross-Talk; Transducción de Señal/genética; Transcriptoma; Microambiente Tumoral

Palabras clave

glioma; molecular classification; receptor tyrosine kinase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fosfoproteínas / Proteínas Tirosina Quinasas Receptoras / Neurofibromina 1 / Péptidos y Proteínas de Señalización Intracelular / Fosfohidrolasa PTEN / Glioma / Proteínas de la Membrana / Proteínas del Tejido Nervioso Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Adult / Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: China

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