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Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis.
Shimizu, Takafumi; Kubovcakova, Lucia; Nienhold, Ronny; Zmajkovic, Jakub; Meyer, Sara C; Hao-Shen, Hui; Geier, Florian; Dirnhofer, Stephan; Guglielmelli, Paola; Vannucchi, Alessandro M; Feenstra, Jelena D Milosevic; Kralovics, Robert; Orkin, Stuart H; Skoda, Radek C.
Afiliación
  • Shimizu T; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
  • Kubovcakova L; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
  • Nienhold R; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
  • Zmajkovic J; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
  • Meyer SC; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
  • Hao-Shen H; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland.
  • Geier F; Bioinformatics Core Facility, Department of Biomedicine, University Hospital Basel, 4031 Basel, Switzerland.
  • Dirnhofer S; Institute of Pathology, University Hospital Basel, 4031 Basel, Switzerland.
  • Guglielmelli P; Department of Clinical and Experimental Medicine, University of Florence, 50134 Florence, Italy.
  • Vannucchi AM; Department of Clinical and Experimental Medicine, University of Florence, 50134 Florence, Italy.
  • Feenstra JD; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.
  • Kralovics R; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria.
  • Orkin SH; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115 Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02215 Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02215.
  • Skoda RC; Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland radek.skoda@unibas.ch.
J Exp Med ; 213(8): 1479-96, 2016 07 25.
Article en En | MEDLINE | ID: mdl-27401344
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hematológicas / Mutación Missense / Proteínas Supresoras de Tumor / Janus Quinasa 2 / Proteína Potenciadora del Homólogo Zeste 2 / Trastornos Mieloproliferativos Límite: Animals Idioma: En Revista: J Exp Med Año: 2016 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hematológicas / Mutación Missense / Proteínas Supresoras de Tumor / Janus Quinasa 2 / Proteína Potenciadora del Homólogo Zeste 2 / Trastornos Mieloproliferativos Límite: Animals Idioma: En Revista: J Exp Med Año: 2016 Tipo del documento: Article País de afiliación: Suiza