Long-Lived Plasma Cells Have a Sweet Tooth.

Corcoran, Lynn M; Nutt, Stephen L

Corcoran, Lynn M; Nutt, Stephen L.

Afiliación

Corcoran LM; The Walter and Eliza Hall Institute of Medical Research, Molecular Immunology Division, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: corcoran@wehi.edu.au.
Nutt SL; The Walter and Eliza Hall Institute of Medical Research, Molecular Immunology Division, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3052, Australia.

Immunity ; 45(1): 3-5, 2016 07 19.

Article en En | MEDLINE | ID: mdl-27438759

ABSTRACT

ABSTRACT

Long-lived plasma cells (LLPCs) are durable antibody-producing cells that are key to immunity. Bhattacharya and colleagues find that LLPCs derive their enhanced survival capacity from a higher rate of glucose import. Some of this glucose sustains the cells through glycolysis, while the bulk is required for antibody glycosylation.

Asunto(s)

Glucólisis; Células Plasmáticas/inmunología; Anticuerpos; Humanos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Plasmáticas / Glucólisis Límite: Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article

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