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The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa, Valeria; Cicardi, Maria Elena; Ramesh, Nandini; Seguin, Samuel J; Ganassi, Massimo; Bigi, Ilaria; Diacci, Chiara; Zelotti, Elena; Baratashvili, Madina; Gregory, Jenna M; Dobson, Christopher M; Cereda, Cristina; Pandey, Udai Bhan; Poletti, Angelo; Carra, Serena.
Afiliación
  • Crippa V; Genomic and post-Genomic Center, C. Mondino National Institute of Neurology Foundation, 27100 Pavia, Italy.
  • Cicardi ME; Dipartimento di Scienze Farmacologiche e Biomolecolari (DiSFeB), Centro di Eccellenza sulle Malattie Neurodegenerative, Università degli Studi di Milano, 20133 Milano, Italy.
  • Ramesh N; Department of Pediatrics, Division of Child Neurology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.
  • Seguin SJ; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA.
  • Ganassi M; Department of Biomedical, Metabolic and Neuronal Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Bigi I; Department of Biomedical, Metabolic and Neuronal Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Diacci C; Department of Biomedical, Metabolic and Neuronal Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Zelotti E; Department of Biomedical, Metabolic and Neuronal Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Baratashvili M; Department of Biomedical, Metabolic and Neuronal Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Gregory JM; Department of Cell Biology, University Medical Center Groningen, Groningen, The Netherlands.
  • Dobson CM; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Cereda C; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Pandey UB; Genomic and post-Genomic Center, C. Mondino National Institute of Neurology Foundation, 27100 Pavia, Italy.
  • Poletti A; Department of Pediatrics, Division of Child Neurology, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.
  • Carra S; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261, USA.
Hum Mol Genet ; 25(18): 3908-3924, 2016 09 15.
Article en En | MEDLINE | ID: mdl-27466192
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Proteínas Serina-Treonina Quinasas / Proteínas de Drosophila / Proteínas de Unión al ADN / Proteínas de Choque Térmico / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2016 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Proteínas Serina-Treonina Quinasas / Proteínas de Drosophila / Proteínas de Unión al ADN / Proteínas de Choque Térmico / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2016 Tipo del documento: Article País de afiliación: Italia