Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment Ameliorate Acetaminophen-Induced Liver Injury in Mice via Central Cholinergic System Regulation.

Zhang, Jianqiao; Zhang, Leiming; Sun, Xue; Yang, Yanting; Kong, Liang; Lu, Chengwen; Lv, Guangyao; Wang, Tian; Wang, Hongbo; Fu, Fenghua

Zhang, Jianqiao; Zhang, Leiming; Sun, Xue; Yang, Yanting; Kong, Liang; Lu, Chengwen; Lv, Guangyao; Wang, Tian; Wang, Hongbo; Fu, Fenghua.

Afiliación

Zhang J; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Zhang L; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Sun X; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Yang Y; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Kong L; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Lu C; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Lv G; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Wang T; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Wang H; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China.
Fu F; Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of Education of China), School of Pharmacy, Yantai University, Yantai, People's Republic of China fufenghua@sohu.com.

J Pharmacol Exp Ther ; 359(2): 374-382, 2016 Nov.

Article en En | MEDLINE | ID: mdl-27535978

Asunto(s)

Acetaminofén/efectos adversos; Enfermedad de Alzheimer/tratamiento farmacológico; Enfermedad Hepática Inducida por Sustancias y Drogas/tratamiento farmacológico; Inhibidores de la Colinesterasa/farmacología; Animales; Enfermedad Hepática Inducida por Sustancias y Drogas/etiología; Enfermedad Hepática Inducida por Sustancias y Drogas/metabolismo; Enfermedad Hepática Inducida por Sustancias y Drogas/patología; Inhibidores de la Colinesterasa/uso terapéutico; Citocinas/metabolismo; Activación Enzimática/efectos de los fármacos; Hígado/efectos de los fármacos; Hígado/metabolismo; Hígado/patología; Masculino; Ratones; Ratones Endogámicos C57BL; Mitocondrias/efectos de los fármacos; Mitocondrias/patología; Proteína Quinasa 9 Activada por Mitógenos/metabolismo; Fosforilación/efectos de los fármacos; Receptores Muscarínicos/metabolismo; Seguridad; Receptor Nicotínico de Acetilcolina alfa 7/metabolismo

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de la Colinesterasa / Enfermedad Hepática Inducida por Sustancias y Drogas / Enfermedad de Alzheimer / Acetaminofén Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: J Pharmacol Exp Ther Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

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