Cathepsin L is crucial for the development of early experimental diabetic nephropathy.

Garsen, Marjolein; Rops, Angelique L W M M; Dijkman, Henry; Willemsen, Brigith; van Kuppevelt, Toin H; Russel, Frans G; Rabelink, Ton J; Berden, Jo H M; Reinheckel, Thomas; van der Vlag, Johan

Garsen, Marjolein; Rops, Angelique L W M M; Dijkman, Henry; Willemsen, Brigith; van Kuppevelt, Toin H; Russel, Frans G; Rabelink, Ton J; Berden, Jo H M; Reinheckel, Thomas; van der Vlag, Johan.

Afiliación

Garsen M; Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands.
Rops AL; Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands.
Dijkman H; Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands.
Willemsen B; Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands.
van Kuppevelt TH; Department of Matrix Biochemistry, Radboud University Medical Center, Nijmegen, the Netherlands.
Russel FG; Department of Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, the Netherlands.
Rabelink TJ; Department of Nephrology, Einthoven Laboratory for Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Berden JH; Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands.
Reinheckel T; Institute of Molecular Medicine and Cell Research and BIOSS Centre for Biological Signaling Studies, Albert-Ludwigs-University, Freiburg, Germany.
van der Vlag J; Department of Nephrology, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: Johan.vanderVlag@radboudumc.nl.

Kidney Int ; 90(5): 1012-1022, 2016 11.

Article en En | MEDLINE | ID: mdl-27575559

Asunto(s)

Catepsina L/metabolismo; Diabetes Mellitus Experimental/complicaciones; Nefropatías Diabéticas/etiología; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Animales; Proteínas del Citoesqueleto/metabolismo; Dinaminas/metabolismo; Glucuronidasa/metabolismo; Ratones Endogámicos C57BL; Proteínas de Microfilamentos/metabolismo

Palabras clave

diabetic nephropathy; glomerulus; proteinuria

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Experimental / Nefropatías Diabéticas / Catepsina L Límite: Animals Idioma: En Revista: Kidney Int Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos

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