Molecular epidemiology and characterization of human coronavirus in Thailand, 2012-2013.
Springerplus
; 5(1): 1420, 2016.
Article
en En
| MEDLINE
| ID: mdl-27625974
ABSTRACT
BACKGROUND:
Coronavirus causes respiratory infections in humans. To determine the prevalence of human coronavirus (HCoV) infection among patients with influenza-like illness, 5833 clinical samples from nasopharyngeal swabs and aspirates collected between January 2012 and December 2013 were examined.RESULTS:
HCoV was found in 46 (0.79 %) samples. There were 19 (0.32 %) HCoV-HKU1, 19 (0.32 %) HCoV-NL63, 5 (0.09 %) HCoV-229E, and 3 (0.05 %) HCoV-OC43. None of the sample tested positive for MERS-CoV. The majority (54 %) of the HCoV-positive patients were between the ages of 0 and 5 years. HCoV was detected throughout the 2-year period and generally peaked from May to October, which coincided with the rainy season. Phylogenetic trees based on the alignment of the spike (S) gene sequences suggest an emergence of a new clade for HCoV-229E.CONCLUSIONS:
The data in this study provide an insight into the prevalence of the recent circulating HCoVs in the region.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Risk_factors_studies
/
Screening_studies
Idioma:
En
Revista:
Springerplus
Año:
2016
Tipo del documento:
Article
País de afiliación:
Tailandia