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Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation.
Wang, Aoli; Yan, Xiao-E; Wu, Hong; Wang, Wenchao; Hu, Chen; Chen, Cheng; Zhao, Zheng; Zhao, Peng; Li, Xixiang; Wang, Li; Wang, Beilei; Ye, Zi; Wang, Jinhua; Wang, Chu; Zhang, Wei; Gray, Nathanael S; Weisberg, Ellen L; Chen, Liang; Liu, Jing; Yun, Cai-Hong; Liu, Qingsong.
Afiliación
  • Wang A; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Yan XE; University of Science and Technology of China, Anhui, Hefei 230036, P. R. China.
  • Wu H; Institute of Systems Biomedicine, Department of Biophysics, Beijing Key Laboratory of Tumor Systems Biology and Center for Molecular and Translational Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P. R. China.
  • Wang W; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Hu C; University of Science and Technology of China, Anhui, Hefei 230036, P. R. China.
  • Chen C; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Zhao Z; Hefei Science Center, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Zhao P; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Li X; University of Science and Technology of China, Anhui, Hefei 230036, P. R. China.
  • Wang L; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Wang B; University of Science and Technology of China, Anhui, Hefei 230036, P. R. China.
  • Ye Z; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Wang J; Hefei Science Center, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Wang C; Institute of Systems Biomedicine, Department of Biophysics, Beijing Key Laboratory of Tumor Systems Biology and Center for Molecular and Translational Medicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P. R. China.
  • Zhang W; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Gray NS; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Weisberg EL; University of Science and Technology of China, Anhui, Hefei 230036, P. R. China.
  • Chen L; High Magnetic Field Laboratory, Chinese Academy of Sciences, Anhui, Hefei 230031, P. R. China.
  • Liu J; University of Science and Technology of China, Anhui, Hefei 230036, P. R. China.
  • Yun CH; Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking-Tsinghua Center for Life Sciences, Peking University, Be
  • Liu Q; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Oncotarget ; 7(43): 69760-69769, 2016 Oct 25.
Article en En | MEDLINE | ID: mdl-27626175
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Inhibidores de Proteínas Quinasas / Receptores ErbB / Mutación Límite: Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Inhibidores de Proteínas Quinasas / Receptores ErbB / Mutación Límite: Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article