The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.

Dahms, Sven O; Creemers, John W M; Schaub, Yvonne; Bourenkov, Gleb P; Zögg, Thomas; Brandstetter, Hans; Than, Manuel E

Dahms, Sven O; Creemers, John W M; Schaub, Yvonne; Bourenkov, Gleb P; Zögg, Thomas; Brandstetter, Hans; Than, Manuel E.

Afiliación

Dahms SO; Protein Crystallography Group, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Beutenbergstr. 11, 07745 Jena, Germany.
Creemers JW; Department of Molecular Biology, University of Salzburg, Billrothstrasse 11, A-5020 Salzburg, Austria.
Schaub Y; Department of Human Genetics, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
Bourenkov GP; Protein Crystallography Group, Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), Beutenbergstr. 11, 07745 Jena, Germany.
Zögg T; European Molecular Biology Laboratory, Hamburg, Germany.
Brandstetter H; Department of Molecular Biology, University of Salzburg, Billrothstrasse 11, A-5020 Salzburg, Austria.
Than ME; Department of Molecular Biology, University of Salzburg, Billrothstrasse 11, A-5020 Salzburg, Austria.

Sci Rep ; 6: 34303, 2016 Sep 27.

Article en En | MEDLINE | ID: mdl-27670069

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

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