Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions.
Biochemistry (Mosc)
; 81(9): 941-50, 2016 Sep.
Article
en En
| MEDLINE
| ID: mdl-27682166
Fibrillarin is one of the most studied nucleolar proteins. Its main functions are methylation and processing of pre-rRNA. Fibrillarin is a highly conserved protein; however, in the course of evolution from archaea to eukaryotes, it acquired an additional N-terminal glycine and arginine-rich (GAR) domain. In this review, we discuss the evolution of fibrillarin structure and its relation to the functions of the protein in prokaryotes and eukaryotes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ARNt Metiltransferasas
/
Proteínas Cromosómicas no Histona
/
Evolución Molecular
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Biochemistry (Mosc)
Año:
2016
Tipo del documento:
Article
País de afiliación:
Rusia
Pais de publicación:
Estados Unidos