Your browser doesn't support javascript.
loading
The P1 biomarker for assessing cortical maturation in pediatric hearing loss: a review.
Sharma, Anu; Glick, Hannah; Deeves, Emily; Duncan, Erin.
Afiliación
  • Sharma A; Brain & Behavior Laboratory, Department of Speech, Language, & Hearing Science and Institute of Cognitive Science, University of Colorado, 2501 Kittredge Loop Road, 409 UCB, Boulder, CO 80309, USA.
  • Glick H; Brain & Behavior Laboratory, Department of Speech, Language, & Hearing Science and Institute of Cognitive Science, University of Colorado, 2501 Kittredge Loop Road, 409 UCB, Boulder, CO 80309, USA.
  • Deeves E; Brain & Behavior Laboratory, Department of Speech, Language, & Hearing Science and Institute of Cognitive Science, University of Colorado, 2501 Kittredge Loop Road, 409 UCB, Boulder, CO 80309, USA.
  • Duncan E; Brain & Behavior Laboratory, Department of Speech, Language, & Hearing Science and Institute of Cognitive Science, University of Colorado, 2501 Kittredge Loop Road, 409 UCB, Boulder, CO 80309, USA.
Otorinolaringologia ; 65(4): 103-114, 2015 Dec.
Article en En | MEDLINE | ID: mdl-27688594
ABSTRACT
We review evidence for a high degree of neuroplasticity of the central auditory pathways in early childhood, citing evidence of studies of the P1 and N1 cortical auditory evoked potentials in congenitally deaf children receiving cochlear implants at different ages during childhood, children with auditory neuropathy spectrum disorder and children with hearing loss and comorbid multiple disabilities. We discuss neuroplasticity, including cortico-cortical de-coupling and cross-modal re-organization that occurs in deafness. We provide evidence for the clinical utility of the P1 cortical auditory evoked potential (CAEP) as a non-invasive biomarker that can be used to objectively assess maturation of auditory cortex in clinical cases of cochlear implant patients and candidates. Finally, we present clinical case studies in which the P1 CAEP biomarker proved useful in clinical decision-making regarding intervention in cases of single-sided deafness, auditory neuropathy spectrum disorder, mild hearing loss and hypoplastic auditory nerve.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Otorinolaringologia Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Otorinolaringologia Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos