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Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis.
Gopal, Pooja; Yee, Michelle; Sarathy, Jickky; Low, Jian Liang; Sarathy, Jansy P; Kaya, Firat; Dartois, Véronique; Gengenbacher, Martin; Dick, Thomas.
Afiliación
  • Gopal P; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore, Republic of Singapore.
  • Yee M; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore, Republic of Singapore.
  • Sarathy J; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore, Republic of Singapore.
  • Low JL; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore, Republic of Singapore.
  • Sarathy JP; Public Health Research Institute, Rutgers-New Jersey Medical School , Newark, New Jersey 07103, United States.
  • Kaya F; Public Health Research Institute, Rutgers-New Jersey Medical School , Newark, New Jersey 07103, United States.
  • Dartois V; Public Health Research Institute, Rutgers-New Jersey Medical School , Newark, New Jersey 07103, United States.
  • Gengenbacher M; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore, Republic of Singapore.
  • Dick T; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore, Republic of Singapore.
ACS Infect Dis ; 2(9): 616-626, 2016 09 09.
Article en En | MEDLINE | ID: mdl-27759369

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazinamida / Proteínas Bacterianas / Coenzima A / Factores de Virulencia / Mycobacterium bovis / Mycobacterium tuberculosis Límite: Humans Idioma: En Revista: ACS Infect Dis Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazinamida / Proteínas Bacterianas / Coenzima A / Factores de Virulencia / Mycobacterium bovis / Mycobacterium tuberculosis Límite: Humans Idioma: En Revista: ACS Infect Dis Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos