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Therapeutics for Brain Metastases, v3.
Steeg, Patricia S; Zimmer, Alexandra; Gril, Brunilde.
Afiliación
  • Steeg PS; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. steegp@mail.nih.gov.
  • Zimmer A; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Gril B; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Clin Cancer Res ; 22(24): 5953-5955, 2016 Dec 15.
Article en En | MEDLINE | ID: mdl-27803066
ABSTRACT
The role of blood-brain barrier (BBB) permeability in the efficacy of brain metastasis therapeutics is debated. Both BBB-permeable and BBB-impermeable compounds were compared in a melanoma brain metastasis model using imaging through a cranial window. Only the BBB-permeable compound inhibited both the ∼30% permeable metastases and the ∼70% impermeable metastases. Clin Cancer Res; 22(24); 5953-5. ©2016 AACRSee related article by Osswald et al., p. 6078.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article