Are Shunt Revisions Associated with IQ in Congenital Hydrocephalus? A Meta -Analysis.
Neuropsychol Rev
; 26(4): 329-339, 2016 12.
Article
en En
| MEDLINE
| ID: mdl-27815765
ABSTRACT
Although it is generally acknowledged that shunt revisions are associated with reductions in cognitive functions in individuals with congenital hydrocephalus, the literature yields mixed results and is inconclusive. The current study used meta-analytic methods to empirically synthesize studies addressing the association of shunt revisions and IQ in individuals with congenital hydrocephalus. Six studies and three in-house datasets yielded 11 independent samples for meta-analysis. Groups representing lower and higher numbers of shunt revisions were coded to generate effect sizes for differences in IQ scores. Mean effect size across studies was statistically significant, but small (Hedges' g = 0.25, p < 0.001, 95 % CI [0.08, 0.43]) with more shunt revisions associated with lower IQ scores. Results show an association of lower IQ and more shunt revisions of about 3 IQ points, a small effect, but within the error of measurement associated with IQ tests. Although clinical significance of this effect is not clear, results suggest that repeated shunt revisions because of shunt failure is associated with a reduction in cognitive functions.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Reoperación
/
Derivaciones del Líquido Cefalorraquídeo
/
Hidrocefalia
/
Inteligencia
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Neuropsychol Rev
Asunto de la revista:
NEUROLOGIA
/
PSICOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos