Risk factors for group B streptococcal disease in neonates of mothers with negative antenatal testing.
J Perinatol
; 37(2): 157-161, 2017 02.
Article
en En
| MEDLINE
| ID: mdl-27853322
ABSTRACT
OBJECTIVE:
The aim of this study was to identify risk factors for early-onset group B Streptococcus (EOGBS) disease in neonates of mothers with negative antenatal screening. STUDYDESIGN:
We performed a retrospective cohort study of neonates born to mothers with negative antenatal GBS screening between 2002 and 2012. Our primary outcome was EOGBS infection. We used multivariable logistic regression to assess factors associated with EOGBS.RESULTS:
EOGBS was confirmed in 492 of the 179 818 neonates that met the study inclusion criteria. Risk factors for EOGBS included black race (reference white, odds ratio (OR) =1.81 (95% confidence interval 1.43, 2.31)), maternal age <18 years (reference >35 years, OR=2.63 (1.54, 4.51)) and maternal age 18 to 35 years (reference >35 years, OR=1.94 (1.30, 2.88)).CONCLUSION:
Maternal age <18 years and black race were the strongest predictors of EOGBS. Further research investigating contributors to the discordance between screening results and neonatal outcomes in these populations is needed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Complicaciones Infecciosas del Embarazo
/
Infecciones Estreptocócicas
/
Edad Materna
/
Transmisión Vertical de Enfermedad Infecciosa
/
Población Negra
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Estados Unidos