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UHPLC-MS/MS bioanalysis of urinary DHEA, cortisone and their hydroxylated metabolites as potential biomarkers for CYP3A-mediated drug-drug interactions.
Zheng, Naiyu; Christopher, Lisa J; Ma, Xuewen; Ji, Qin C; Buzescu, Adela; Kandoussi, Hamza; Garonzik, Samira M; LaCreta, Frank; Aubry, Anne-Francoise; Arnold, Mark E; Zeng, Jianing.
Afiliación
  • Zheng N; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Christopher LJ; Pharmaceutical Candidate Optimization, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Ma X; Early Clinical & Translational Research, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Ji QC; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Buzescu A; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Kandoussi H; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Garonzik SM; Early Clinical & Translational Research, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • LaCreta F; Early Clinical & Translational Research, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Aubry AF; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Arnold ME; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
  • Zeng J; Analytical & Bioanalytical Operations, Bristol-Myers Squibb Company, Princeton, NJ 08543, USA.
Bioanalysis ; 8(23): 2429-2443, 2016 Dec.
Article en En | MEDLINE | ID: mdl-27855510
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cortisona / Biomarcadores / Urinálisis / Deshidroepiandrosterona / Citocromo P-450 CYP3A / Espectrometría de Masas en Tándem Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioanalysis Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cortisona / Biomarcadores / Urinálisis / Deshidroepiandrosterona / Citocromo P-450 CYP3A / Espectrometría de Masas en Tándem Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Bioanalysis Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido