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Prospective cohort study assessing chronic pain in patients following minor surgery for breast cancer.
Fuzier, Régis; Puel, Floriane; Izard, Philippe; Sommet, Agnès; Pierre, Sébastien.
Afiliación
  • Fuzier R; Department of Anesthesiology, Institut Claudius Regaud. University Institute of Cancer Toulouse Oncopole, 1 Avenue Irène Joliot-Curie, 31059, Toulouse Cedex, France. fuzier.r@gmail.com.
  • Puel F; Department of Anesthesiology, Institut Claudius Regaud. University Institute of Cancer Toulouse Oncopole, 1 Avenue Irène Joliot-Curie, 31059, Toulouse Cedex, France.
  • Izard P; Department of Anesthesiology, Institut Claudius Regaud. University Institute of Cancer Toulouse Oncopole, 1 Avenue Irène Joliot-Curie, 31059, Toulouse Cedex, France.
  • Sommet A; Pharmacoepidemiology Research Unit, INSERM 1027, University of Toulouse, Toulouse, France.
  • Pierre S; Department of Anesthesiology, Institut Claudius Regaud. University Institute of Cancer Toulouse Oncopole, 1 Avenue Irène Joliot-Curie, 31059, Toulouse Cedex, France.
J Anesth ; 31(2): 246-254, 2017 Apr.
Article en En | MEDLINE | ID: mdl-27885426
PURPOSE: Pain after tumorectomy and sentinel lymph node dissection is poorly reported in the literature. We carried out a prospective survey aimed at assessing pain three months after such minor surgery for breast cancer. METHODS: The study was approved by the local ethics committee. Most surgeries followed a standard protocol involving general anesthesia with no regional analgesia technique, laryngeal mask, sufentanil and propofol for induction, and multimodal analgesia during the postoperative period. Three months after the surgery, a questionnaire was sent to the patients with a pre-stamped envelope for return. The questions probed responses required to calculate a Brief Pain Inventory score and modified neuropathic pain score (DN3). RESULTS: Over a 5-month period, 150 patients (aged 60 (11) years, body mass index of 25 (6) kg/m2) were included in the final analysis. In the recovery room, 43% of patients required morphine at a mean dose of 5.2 (1.8) mg. Three months post surgery, 60 patients (40%) reported persistent pain for which 62% took analgesic drugs. We found no risk factor associated with this persistent pain among our studied population. Neuropathic pain was noted in 61% of patients who reported persistent pain primarily associated with periareolar incision. CONCLUSIONS: Pain persisted up to three months after minor surgery for breast cancer in 40% of patients with mostly a neuropathic component (61%).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Neoplasias de la Mama / Dolor Crónico / Neuralgia Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Aspecto: Ethics Límite: Aged / Female / Humans / Middle aged Idioma: En Revista: J Anesth Asunto de la revista: ANESTESIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Neoplasias de la Mama / Dolor Crónico / Neuralgia Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Aspecto: Ethics Límite: Aged / Female / Humans / Middle aged Idioma: En Revista: J Anesth Asunto de la revista: ANESTESIOLOGIA Año: 2017 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Japón