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Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles.
Huang, Hai; Shi, Hongdong; Liu, Jing; Min, Yuanzeng; Wang, Yucai; Wang, Andrew Z; Wang, Jun; Liu, Yangzhong.
Afiliación
  • Huang H; CAS Key Laboratory of Soft Matter Chemistry, CAS High Magnetic Field Laboratory, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. liuyz@ustc.edu.cn.
  • Shi H; CAS Key Laboratory of Soft Matter Chemistry, CAS High Magnetic Field Laboratory, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. liuyz@ustc.edu.cn.
  • Liu J; School of Life Sciences, University of Science and Technology of China, China.
  • Min Y; Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
  • Wang Y; School of Life Sciences, University of Science and Technology of China, China.
  • Wang AZ; Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
  • Wang J; School of Life Sciences, University of Science and Technology of China, China.
  • Liu Y; CAS Key Laboratory of Soft Matter Chemistry, CAS High Magnetic Field Laboratory, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. liuyz@ustc.edu.cn.
Chem Commun (Camb) ; 53(1): 212-215, 2016 12 20.
Article en En | MEDLINE | ID: mdl-27918025
Co-delivery of all-trans-retinoic acid and paclitaxel using albumin-bound nanoparticles demonstrated a significantly improved anti-metastatic effect to breast cancer both in vitro and in vivo. Notably, the co-delivery nanoparticles exhibited more pronounced therapeutic effects than the combination of two free drugs or two HSA loaded single drugs.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tretinoina / Portadores de Fármacos / Nanopartículas / Paclitaxel Unido a Albúmina / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Buscar en Google
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tretinoina / Portadores de Fármacos / Nanopartículas / Paclitaxel Unido a Albúmina / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido