Syndrome of inappropriate antidiuretic hormone secretion in a case of olfactory neuroblastoma without anti-diuretic hormone immunoreactivity: A case report and review of the literature.
Auris Nasus Larynx
; 44(6): 771-774, 2017 Dec.
Article
en En
| MEDLINE
| ID: mdl-28010942
ABSTRACT
Olfactory neuroblastoma (ONB) is a relatively rare nasal or paranasal malignant tumor. This tumor is rarely accompanied by paraneoplastic syndromes such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). Here, we report a 31-year-old female with histologically confirmed ONB who had been diagnosed with SIADH three years prior. She was treated with surgery followed by concurrent chemoradiotherapy. SIADH resolved immediately after surgical tumor resection. Immunohistochemically, both biopsy and resected specimens from the nasal cavity had been negative for ADH. Although extremely rare, ONB may be associated with SIADH, and the possibility of this cancer should be taken into account during the follow-up of idiopathic SIADH.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Nasales
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Estesioneuroblastoma Olfatorio
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Síndrome de Secreción Inadecuada de ADH
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Cavidad Nasal
Tipo de estudio:
Etiology_studies
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Auris Nasus Larynx
Año:
2017
Tipo del documento:
Article