Malignant Oestrogen-producing Teratoma in a Cat.
J Comp Pathol
; 156(2-3): 178-182, 2017.
Article
en En
| MEDLINE
| ID: mdl-28017339
ABSTRACT
A 5-year-old female domestic shorthair cat was presented with abdominal distension and serum biochemical evaluation indicated a high concentration of oestradiol (32.81 pg/ml). Exploratory laparotomy revealed a large cystic mass in the right ovary with cystic fluid containing a high level of oestradiol (18.80 pg/ml). The tumour was composed of immature neuroectodermal tissue, mature cartilage, smooth muscle, adipose tissue and aggregated, poorly differentiated mesenchymal cells. It contained cysts of various sizes that were lined by epithelium of different types. The basal layer of the lining epithelium was shown to express aromatase by immunohistochemistry. The findings suggest that this was a novel, malignant, oestrogen-secreting teratoma and that the aromatase-positive, neoplastic cells may have been the source of elevated levels of serum oestrogen.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Teratoma
/
Enfermedades de los Gatos
/
Estrógenos
Límite:
Animals
Idioma:
En
Revista:
J Comp Pathol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Japón