Development of Left Atrial Thrombus After Coadministration of Dabigatran Etexilate and Phenytoin.
Can J Cardiol
; 33(4): 554.e13-554.e14, 2017 04.
Article
en En
| MEDLINE
| ID: mdl-28063739
ABSTRACT
Dabigatran etexilate is a substrate of the P-glycoprotein (adenosine triphosphate-binding cassette subfamily B member 1) transport system and is subject to interactions with medications that induce or inhibit this system. The clinical relevance of the interaction between dabigatran and phenytoin has not been well described. We report a case of left atrial thrombus in a patient receiving concomitant dabigatran etexilate and phenytoin, which is a P-glycoprotein inducer. This case illustrates the potential clinical significance of the interactions of medications that affect P-glycoprotein and dabigatran.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fenitoína
/
Trombosis
/
Dabigatrán
/
Cardiopatías
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Can J Cardiol
Asunto de la revista:
CARDIOLOGIA
Año:
2017
Tipo del documento:
Article