[The individual and combined antioxidant effects of citicoline and ethylmethylhydroxypyridini succinas]. / Individual'nye i kombinirovannye antioksidantnye effekty tsitikolina i etilmetilgidroksipiridina suktsinata.
Zh Nevrol Psikhiatr Im S S Korsakova
; 116(11): 78-85, 2016.
Article
en Ru
| MEDLINE
| ID: mdl-28091505
ABSTRACT
AIM:
To study the antioxidant status of patients with chronic cerebral ischemia (CCI) during the individual treatment with 2-ethyl-6-methyl-3-hydroxypyridine-succinate (neurox) and in the combination with citicoline (neipilept). MATERIAL ANDMETHODS:
A study included 40 patients, 18 men and 22 women, aged from 54 to 72 years, with CCI, stage 2, at the decompensation stage complicated with the hypertensive crisis and/or arrhythmia. RESULTS ANDCONCLUSION:
A significant increase in the serum superoxide dismutase activity after the complex therapy with neurox and neipilept was demonstrated compared to patients treated with neurox. A study of reduced sulfur-hydroxy groups in patients treated with 2-ethyl-6-methyl-3-hydroxypyridine-succinate and patients treated with the combination of 2-ethyl-6-methyl-3-hydroxypyridine-succinate and citicoline, revealed a significant increase in the number of reduced SH- groups after the treatment with neurox compared to the combined use of neurox and neipilept.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Picolinas
/
Isquemia Encefálica
/
Citidina Difosfato Colina
/
Antioxidantes
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Zh Nevrol Psikhiatr Im S S Korsakova
Asunto de la revista:
NEUROLOGIA
/
PSIQUIATRIA
Año:
2016
Tipo del documento:
Article
Pais de publicación:
FEDERAÇÃO RUSSA
/
RU
/
RUSIA
/
RUSSIA