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Identification of a novel selective PPARγ ligand with a unique binding mode and improved therapeutic profile in vitro.
Yi, Wei; Shi, Jingjing; Zhao, Guanguan; Zhou, X Edward; Suino-Powell, Kelly; Melcher, Karsten; Xu, H Eric.
Afiliación
  • Yi W; School of Pharmaceutical Sciences, Guangzhou Medical University, Xinzao, Panyu District, Guangzhou 511436, P. R. China.
  • Shi J; VARI/SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China.
  • Zhao G; VARI/SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China.
  • Zhou XE; VARI/SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China.
  • Suino-Powell K; Laboratory of Structural Sciences, Program of Structural Biology and Drug Discovery, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Melcher K; Laboratory of Structural Sciences, Program of Structural Biology and Drug Discovery, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
  • Xu HE; Laboratory of Structural Sciences, Program of Structural Biology and Drug Discovery, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.
Sci Rep ; 7: 41487, 2017 01 27.
Article en En | MEDLINE | ID: mdl-28128331
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: PPAR gamma / Indoles Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: PPAR gamma / Indoles Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article Pais de publicación: Reino Unido