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A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging.
Doria, F; Nadai, M; Zuffo, M; Perrone, R; Freccero, M; Richter, S N.
Afiliación
  • Doria F; Dept. of Chemistry, University of Pavia, V.le Taramelli 10, 27100 Pavia, Italy. mauro.freccero@unipv.it.
  • Nadai M; Dept. of Molecular Medicine, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.
  • Zuffo M; Dept. of Chemistry, University of Pavia, V.le Taramelli 10, 27100 Pavia, Italy. mauro.freccero@unipv.it.
  • Perrone R; Dept. of Molecular Medicine, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.
  • Freccero M; Dept. of Chemistry, University of Pavia, V.le Taramelli 10, 27100 Pavia, Italy. mauro.freccero@unipv.it.
  • Richter SN; Dept. of Molecular Medicine, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.
Chem Commun (Camb) ; 53(14): 2268-2271, 2017 Feb 14.
Article en En | MEDLINE | ID: mdl-28149992
Aggregation, red-NIR emission and light-up upon nucleic acid G-quadruplex binding have been investigated for a prototype core-extended naphthalene diimide, which is capable of fast cellular entry and nucleolar localization. Both high-level colocalization with an anti-G-quadruplex antibody and nucleolin displacement reveal that the compound targets and thus makes visible nuclear DNA G-quadruplexes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: G-Cuádruplex / Colorantes Fluorescentes Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: G-Cuádruplex / Colorantes Fluorescentes Límite: Humans Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido