Rapid diagnostics of urinary iodine using a portable EDXRF spectrometer.
J Xray Sci Technol
; 25(3): 515-521, 2017.
Article
en En
| MEDLINE
| ID: mdl-28157117
ABSTRACT
A method for urinary iodine diagnostics using a portable energy-dispersion X-ray fluorescent (EDXRF) spectrometer is proposed. The principle of the method consists in excitation of the sample atoms fluorescence by the energy spectrum intentionally formed from the spectrum of an X-ray tube using an optimized X-ray scheme. The optimization by the criterion of the minimum detection limit for L-series iodine fluorescence lines included the calculation of optimal atomic numbers for materials of a re-radiator and a filter, and their thicknesses, the collimation system parameters, and an X-ray tube voltage. Experimentally achieved detection limits were 45 and 75 µg/L by I-Lα and I-Lß lines, respectively, at the theoretically extreme value 30 µg/L. This sensitivity is found to be sufficient for urinary iodine diagnostics in the range from 50 to 200 µg/L. The results obtained from different patients have shown the satisfactory convergence for the iodine concentration determination by Lα and I-Lß fluorescence lines. The simple sample preparation procedure and comparably small sizes of the apparatus allows rapid researches directly in clinical settings.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Espectrometría por Rayos X
/
Yodo
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
J Xray Sci Technol
Asunto de la revista:
RADIOLOGIA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Ucrania