Analysis of chromosomal radiosensitivity of healthy BRCA2 mutation carriers and non-carriers in BRCA families with the G2 micronucleus assay.

Baert, Annelot; Depuydt, Julie; Van Maerken, Tom; Poppe, Bruce; Malfait, Fransiska; Van Damme, Tim; De Nobele, Sylvia; Perletti, Gianpaolo; De Leeneer, Kim; Claes, Kathleen B M; Vral, Anne

Baert, Annelot; Depuydt, Julie; Van Maerken, Tom; Poppe, Bruce; Malfait, Fransiska; Van Damme, Tim; De Nobele, Sylvia; Perletti, Gianpaolo; De Leeneer, Kim; Claes, Kathleen B M; Vral, Anne.

Afiliación

Baert A; Department of Basic Medical Sciences, Ghent University, B-9000 Ghent, Belgium.
Depuydt J; Department of Basic Medical Sciences, Ghent University, B-9000 Ghent, Belgium.
Van Maerken T; Department of Pediatrics and Medical Genetics, Ghent University, B-9000 Ghent, Belgium.
Poppe B; Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium.
Malfait F; Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium.
Van Damme T; Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium.
De Nobele S; Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium.
Perletti G; Department of Basic Medical Sciences, Ghent University, B-9000 Ghent, Belgium.
De Leeneer K; Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium.
Claes KB; Center for Medical Genetics, Ghent University Hospital, B-9000 Ghent, Belgium.
Vral A; Department of Basic Medical Sciences, Ghent University, B-9000 Ghent, Belgium.

Oncol Rep ; 37(3): 1379-1386, 2017 Mar.

Article en En | MEDLINE | ID: mdl-28184943

Asunto(s)

Proteína BRCA1/genética; Proteína BRCA2/genética; Rotura Cromosómica/efectos de la radiación; Pruebas de Micronúcleos/métodos; Mutación/genética; Tolerancia a Radiación/genética; Adulto; Femenino; Predisposición Genética a la Enfermedad; Voluntarios Sanos; Humanos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Pruebas de Micronúcleos / Proteína BRCA1 / Rotura Cromosómica / Proteína BRCA2 / Mutación Límite: Adult / Female / Humans Idioma: En Revista: Oncol Rep Asunto de la revista: NEOPLASIAS Año: 2017 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Grecia

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